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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNE1
All Species:
13.57
Human Site:
S404
Identified Species:
22.97
UniProt:
P24864
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24864
NP_001229.1
410
47077
S404
P
Q
S
G
K
K
Q
S
S
G
P
E
M
A
_
Chimpanzee
Pan troglodytes
XP_512559
393
44800
Q386
P
P
Q
S
G
K
K
Q
S
S
G
P
E
M
A
Rhesus Macaque
Macaca mulatta
XP_001084995
410
47103
S404
P
Q
S
S
K
K
Q
S
S
E
P
E
M
A
_
Dog
Lupus familis
XP_541724
456
51105
S450
P
Q
S
S
K
K
Q
S
S
G
Q
D
T
A
_
Cat
Felis silvestris
Mouse
Mus musculus
Q61457
408
46968
S402
P
P
S
S
K
K
Q
S
S
E
Q
E
T
E
_
Rat
Rattus norvegicus
P39949
411
47463
S405
P
H
S
S
K
K
Q
S
S
E
Q
E
T
E
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507249
405
46635
T393
V
C
N
G
G
I
M
T
P
P
T
S
T
E
K
Chicken
Gallus gallus
P49707
407
46720
P401
P
Q
S
S
K
K
Q
P
A
G
L
K
P
I
_
Frog
Xenopus laevis
Q91780
408
47153
Zebra Danio
Brachydanio rerio
P47794
410
46612
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54733
709
77202
D668
E
Y
L
G
D
E
G
D
E
T
G
A
R
S
G
Honey Bee
Apis mellifera
XP_394802
457
51232
G431
R
Q
S
P
N
E
S
G
L
L
T
P
P
S
S
Nematode Worm
Caenorhab. elegans
O01501
524
60567
I510
V
K
S
E
R
E
R
I
Q
H
L
K
A
R
R
Sea Urchin
Strong. purpuratus
XP_785047
424
48468
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
98.2
73.9
N.A.
78.7
79.5
N.A.
49
71.9
60.2
58.2
N.A.
28.2
38.2
24.2
44.5
Protein Similarity:
100
95.3
98.5
81.1
N.A.
88.7
90
N.A.
66.5
85.1
76.8
73.9
N.A.
39.6
55.1
41.4
60.8
P-Site Identity:
100
20
85.7
71.4
N.A.
57.1
57.1
N.A.
6.6
50
0
0
N.A.
6.6
13.3
6.6
0
P-Site Similarity:
100
26.6
85.7
78.5
N.A.
57.1
57.1
N.A.
20
64.2
0
0
N.A.
26.6
26.6
40
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
8
0
0
8
8
22
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% D
% Glu:
8
0
0
8
0
22
0
0
8
22
0
29
8
22
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
22
15
0
8
8
0
22
15
0
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
8
0
0
0
0
0
8
0
% I
% Lys:
0
8
0
0
43
50
8
0
0
0
0
15
0
0
8
% K
% Leu:
0
0
8
0
0
0
0
0
8
8
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
15
8
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
15
0
8
0
0
0
8
8
8
15
15
15
0
0
% P
% Gln:
0
36
8
0
0
0
43
8
8
0
22
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
8
0
0
0
0
0
8
8
8
% R
% Ser:
0
0
58
43
0
0
8
36
43
8
0
8
0
15
8
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
15
0
29
0
0
% T
% Val:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
43
% _